Serum ferritin and transferrin saturation levels in β0 and β+ thalassemia patients
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چکیده
منابع مشابه
Serum ferritin and transferrin saturation levels in β⁰ and β(+) thalassemia patients.
There have been few studies on the mutations that cause heterozygous beta-thalassemia and how they affect the iron profile. One hundred and thirty-eight individuals were analyzed, 90 thalasemic β⁰ and 48 thalasemic β(+), identified by classical and molecular methods. Mutations in the hemochromatosis (HFE) gene, detected using PCR-RFLP, were found in 30.4% of these beta-thalassemic patients; het...
متن کاملCorrelation between Heart and Liver Iron Levels Measured by MRI T2* and Serum Ferritin in Patients with β-thalassemia Major
Background Transfusion-induced iron overload leads to many complications in patients with β-thalassemia major. This study aimed to compare the level of iron stored in the liver and heart measured by MRI T2 * with ferritin levels in these patients. Materials and Methods This study was done on 52 patients with β-thalassemia major aged 7 to 29 years. Serum ferritin level was checked and heart and ...
متن کاملAssociation between serum ferritin level and diastolic cardiac function in patients with major β-thalassemia
Abstract Background Prevention of myocardial siderosis is a key step to reduce rate of mortality in thalassemic patients. Our objective was to study association between echocardiography parameters and serum ferritin level in patients with major thalassemia. Materials and Methods Sixty-six patients with major thalassemia were studied in Amir Kabir hospital, Arak, Iran. Serum ferritin levels ...
متن کاملSerum ferritin and transferrin saturation in Asians and Pacific Islanders.
BACKGROUND Asians and Pacific Islanders in the Hemochromatosis and Iron Overload Screening (HEIRS) Study had the highest prevalence of elevated serum ferritin (SF) and transferrin saturation (TS) levels, but to our knowledge, the reasons for this have not been investigated. METHODS Using multiple linear regression, we compared TS and SF distributions for 42 720 Asian, Pacific Islander, and wh...
متن کاملRelation between bone mineral density and serum ferritin levels in patients with thalassemia major
Background: Thalassemia/haemoglobinopathy is a hereditary disease with increased erythropoiesis and expansion of the bone marrow cavity. Consequently, there is a reduction in trabecular bone tissue resulting in osteopenia/osteoporosis. The present study was performed to determine bone mineral density (BMD) in children and adolescents with major thalassemia and its correlation with serum fer...
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ژورنال
عنوان ژورنال: Genetics and Molecular Research
سال: 2011
ISSN: 1676-5680
DOI: 10.4238/vol10-2gmr1016